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IKKgamma NEMO Binding Domain (NBD) Inhibitory Peptide

IKKgamma NEMO Binding Domain (NBD) Inhibitory Peptide

Item no.	AS-61169
Manufacturer	AnaSpec
Amount	1 mg
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Conjugate/Tag	Unconjugated
Purity	Peak Area by HPLC ≥95%
Sequence	H-Asp-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Thr-Ala-Leu-Asp-Trp-Ser-Trp-Leu-Gln-Thr-Glu-OH
Citations	Ref: Paria, B. et al. J. Biol. Chem. 278, 37195 (2003); Tian, M. et al. Blood May 2005(10.1182/blood-2004-04-1248); Bharti, A. Blood 101, 1053 (2003).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	DRQIKIWFQNRRMKWKKTALDWSWLQTE
Shipping Condition	Room temperature
Available
Manufacturer - Category	Catalog Peptides / Catalog Peptides Gr / Peptides
Manufacturer - Targets	NEMO
Shipping Temperature	RT
Storage Conditions	- 20 °C
Molecular Weight	3693.5
Manufacturer - Research Area	Cell Permeable & Penetrating peptides / Other CPP Peptides
Description	A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF-alpha-induced NF-kB activation. The interaction of IK?NEMO with the IKK complex is critical for the activation of the IKK complex and the subsequent activation of NF-kB.
Sequence One-Letter Code	DRQIKIWFQNRRMKWKKTALDWSWLQTE
Post Synthesis Coupling	No
Usage	Research use
UNSPSC	12352202
GTIN	5400535154844

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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AS-61169-safety-datasheet.pdf