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IKKgamma NEMO Binding Domain (NBD) Inhibitory Peptide - 1 mg

IKKgamma NEMO Binding Domain (NBD) Inhibitory Peptide - 1 mg

Item no.	AS-61169
Manufacturer	AnaSpec
Amount	1 mg
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Conjugate/Tag	Unconjugated
Purity	Peak Area by HPLC ≥95%
Sequence	H-Asp-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Thr-Ala-Leu-Asp-Trp-Ser-Trp-Leu-Gln-Thr-Glu-OH
Citations	Ref: Paria, B. et al. J. Biol. Chem. 278, 37195 (2003); Tian, M. et al. Blood May 2005(10.1182/blood-2004-04-1248); Bharti, A. Blood 101, 1053 (2003).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	DRQIKIWFQNRRMKWKKTALDWSWLQTE
Shipping Condition	Room temperature
Available
Manufacturer - Type	Catalog
Manufacturer - Category	Peptides
Manufacturer - Targets	NEMO
Shipping Temperature	RT
Storage Conditions	- 20 °C
Molecular Weight	3693.5
Description	A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF-alpha-induced NF-kB activation. The interaction of IKgammaNEMO with the IKK complex is critical for the activation of the IKK complex and the subsequent activation of NF-kB.
Product Group	LB1A1Z
Research Area	Cell Permeable & Penetrating peptides / Lyophilized
Sequence One-Letter Code	DRQIKIWFQNRRMKWKKTALDWSWLQTE
GTIN	5400535154844
Usage	Research use
UNSPSC	12352202

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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AS-61169-safety-datasheet.pdf