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MUC5AC-3

MUC5AC-3

Item no.	AS-61334
Manufacturer	AnaSpec
Amount	1 mg
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Conjugate/Tag	Unconjugated
Purity	Peak Area by HPLC ≥95%
Sequence	H-Gly-Thr-Thr-Pro-Ser-Pro-Val-Pro-Thr-Thr-Ser-Thr-Thr-Ser-Ala-Pro-OH (Thr = GalNAc labeled Thr)
Citations	Duperat, V. et al. Biochem. J. 305, 211 (1995); Ten Hagen, K. et al. J. Biol. Chem. 277, 22616 (2002); Van Klinken, B. et al. Am. J. Physiol. Gastrointest. Liver Physiol. 276, G115 (1999); Ten Hagen, K. et al. Glycobiol. 13, 1R (2003).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	GT-T*-PSPVPTTSTTSAP
Shipping Condition	Room temperature
Available
Manufacturer - Category	Catalog Peptides / Catalog Peptides Gr / Peptides
Manufacturer - Targets	Mucin
Shipping Temperature	RT
Storage Conditions	- 20 °C
Molecular Weight	1704.9
Manufacturer - Research Area	Cancer & Apoptosis / Oncogenesis
Description	This glycopeptide is a 16-amino acid modified fragment of mucin 5/MUC5AC, where T* is a GalNac labeled threonine 3. Mucin-type linkages (GalNAc 1-O-Ser/Thr) are initiated by a family of glycosyltransferases known as the UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferases (ppGaNTases). These enzymes transfer GalNAc from the sugar donor UDP-GalNAc to serine and threonine residues, forming an alpha anomeric linkage. The MUC5AC gene, which is mainly expressed in gastric and respiratory mucosae, exhibits 8 amino acid tandemly repeated domain, the consensus peptide TTSTTSAP.
Sequence One-Letter Code	GT-T-PSPVPTTSTTSAP ( = GalNAc-modified residue)
Post Synthesis Coupling	No
Usage	Research use
UNSPSC	12352202
GTIN	5400535154011

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AS-61334-safety-datasheet.pdf