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HIF-1a (556-574)

HIF-1a (556-574)

Item no.	AS-61528
Manufacturer	AnaSpec
Amount	1 mg
Category	Oncology By Cell Type Carcinoma Hematology Lymphoma Melanoma Sarcoma Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Conjugate/Tag	Unconjugated
Purity	Peak Area by HPLC ≥95%
Sequence	H-Asp-Leu-Asp-Leu-Glu-Met-Leu-Ala-Pro-Tyr-Ile-Pro-Met-Asp-Asp-Asp-Phe-Gln-Leu-OH
Citations	Ref: Hirsilä, M. et al. J Biol. Chem 278, 30772 (2003); Robinson, B. Pediatric Research 50, 673 (2001).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	DLDLEMLAPYIPMDDDFQL
Shipping Condition	Room temperature
Available
Manufacturer - Category	Catalog Peptides / Catalog Peptides Gr / Peptides
Manufacturer - Targets	Hypoxia-Inducible Factor-1 (HIF-1 a)
Shipping Temperature	RT
Storage Conditions	- 20 °C
Molecular Weight	2254.7
Manufacturer - Research Area	Cancer & Apoptosis; Cardiovascular Research / Oncogenesis; Angiogenesis
Description	This is a hypoxia-inducible factor-1 (HIF-1 a) 19-mer fragment. HIF-1 functions as a master regulator of response to oxygen homeostasis. Hypoxia-induced gene expression is initiated when HIF-1 subunit is stabilized in response to a lack of oxygen. This part of HIF-1 binds to the von Hippel-Lindau factor (VHL) an E3 ubiquitin ligase, and the proline 564 is absolutely critical to the binding process.
Sequence One-Letter Code	DLDLEMLAPYIPMDDDFQL
Post Synthesis Coupling	No
Usage	Research use
UNSPSC	12352202
GTIN	5400535152567

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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AS-61528-safety-datasheet.pdf