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HIF-1a (556-574) - 1 mg

HIF-1a (556-574) - 1 mg

Item no.	AS-61528
Manufacturer	AnaSpec
Amount	1 mg
Category	Oncology By Cell Type Carcinoma Hematology Lymphoma Melanoma Sarcoma Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Purity	Peak Area by HPLC ≥95%
Sequence	H-Asp-Leu-Asp-Leu-Glu-Met-Leu-Ala-Pro-Tyr-Ile-Pro-Met-Asp-Asp-Asp-Phe-Gln-Leu-OH
Citations	Ref: Hirsilä, M. et al. J Biol. Chem 278, 30772 (2003); Robinson, B. Pediatric Research 50, 673 (2001).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	DLDLEMLAPYIPMDDDFQL
Shipping Condition	Room temperature
Available
Manufacturer - Type	Catalog
Manufacturer - Category	Peptides
Manufacturer - Targets	Hypoxia-Inducible Factor-1 (HIF-1 a)
Shipping Temperature	RT
Storage Conditions	- 20 °C
Molecular Weight	2254.7
Description	This is a hypoxia-inducible factor-1 (HIF-1 a) 19-mer fragment. HIF-1 functions as master regulator of response to oxygen homeostasis. Hypoxia-induced gene expression is initiated when HIF-1 subunit is stabilized in response to a lack of oxygen. This part of HIF-1 binds to the von Hippel-Lindau factor (VHL) an E3 ubiquitin ligase, and the proline 564 is absolutely critical to the binding process
Product Group	LB1A1Z
Research Area	Cancer & Apoptosis; Cardiovascular Research / Lyophilized
Sequence One-Letter Code	DLDLEMLAPYIPMDDDFQL
GTIN	5400535152567
Usage	Research use
UNSPSC	12352202

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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AS-61528-safety-datasheet.pdf