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Protease-Activated Receptor-1, PAR-1 Agonist

Protease-Activated Receptor-1, PAR-1 Agonist

Item no.	AS-61530
Manufacturer	AnaSpec
Amount	1 mg
Category	Neuroscience Molecular Targets for Neuroscience Peptides & Proteins Cardiovascular Research Thrombosis & Hemostasis Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Conjugate/Tag	Unconjugated
Purity	Peak Area by HPLC ≥95%
Sequence	H-Thr-Phe-Leu-Leu-Arg-Asn-OH
Citations	Ref: Syeda,, F. et al. J. Biol. Chem 281, 11792 (2006); Jenkins, R. et al. J. Clin. Invest; 116, 1606 (2006).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	TFLLRN
Shipping Condition	Room temperature
Available
Manufacturer - Category	Catalog Peptides / Catalog Peptides Gr / Peptides
Manufacturer - Targets	Protease-Activated Receptor (PAR)
Shipping Temperature	RT
Storage Conditions	- 20 °C
Molecular Weight	762.9
Manufacturer - Research Area	Cardiovascular Research; Cell Signaling / Coagulation; GPCR
Description	Protease activated receptor 1 (PAR-1) belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. This protease-activated receptor-1 (PAR-1) selective peptide induces cyclooxygenase-2 (COX-2) protein and mRNA expression in human endothelial cells. Studies show that intratracheal instillation of the PAR1-specific peptide increases lung edema during high-tidal-volume ventilation
Sequence One-Letter Code	TFLLRN
Post Synthesis Coupling	No
Usage	Research use
UNSPSC	12352202
GTIN	5400535152550

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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AS-61530-safety-datasheet.pdf