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Cathepsin D and E FRET Substrate - 1 mg

Cathepsin D and E FRET Substrate - 1 mg

Item no.	AS-61793
Manufacturer	AnaSpec
Amount	1 mg
Category	Oncology Neuroscience Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Peptides & Proteins Cell Biology Cell Status Apoptosis Peptides By Organ Breast Cancer Testicular & Prostate Cancer
Type	Peptides
Format	Lyophilized
Specific against	other
Conjugate/Tag	Unconjugated
Purity	Peak Area by HPLC ≥95%
Sequence	7-Methoxycoumarin-4-Acetyl-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys(Dnp)-D-Arg-NH2
Citations	Yasuda, Y. et al. J. Biochem. 125, 1137 (1999).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Mca-GKPILFFRLK(Dnp)-r-NH2
Shipping Condition	Room temperature
Available
Manufacturer - Type	Catalog
Manufacturer - Applications	Enzyme activity
Manufacturer - Category	Peptides
Manufacturer - Targets	Cathepsin; Cathepsin D; Cathepsin E
Manufacturer - Conjugate / Tag	MCA-Dnp
Shipping Temperature	RT
Storage Conditions	- 20 °C Protected from light
Molecular Weight	1756.1
Description	An internally quenched fluorogenic substrate (Ab/Em =328/393 nm) for cathepsins D and E and not for B, H or L, obtained from the hepatopancreas (liver) of the Japanese common squid (Todarodes pacificus). The cleavage occurs at the Phe-Phe amide bond resulting in enhanced fluorescence and is used in screening cathepsin D and E inhibitors and for determining cathepsin D and E activity in tissue cell extracts.
Product Group	LB1A3Z
Research Area	Cell Signaling; Cancer & Apoptosis; Neuroscience / Lyophilized
Absorbtion (nm)	328
Emission (nm)	393
Sequence One-Letter Code	Mca-GKPILFFRLK(Dnp)-r-NH2
GTIN	5400535151188
Detection Method	Fluorescent
Usage	Research use
UNSPSC	12352202

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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AS-61793-safety-datasheet.pdf