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Histone deacetylase, HDAC substrate

Histone deacetylase, HDAC substrate

Item no.	AS-61855
Manufacturer	AnaSpec
CASRN	660846-97-9
Amount	1 mg
Category	Neuroscience Neural Epigenetics Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Purity	Peak Area by HPLC ≥95%
Sequence	Ac-Arg-Gly-Lys(Ac)-AMC
Citations	Wegener, D. et al. Chem. Biol. 10, 61 (2003).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Ac-RGK(Ac)-AMC
Shipping Condition	Room temperature
Available
Manufacturer - Applications	Enzyme activity
Manufacturer - Category	Catalog Peptides / Catalog Peptides Gr / Peptides / Labeling & detection / Blue (<500 nm)
Manufacturer - Targets	Histone deacetylase (HDAC)
Manufacturer - Conjugate / Tag	Fluorescent dyes: AMC
Shipping Temperature	RT
Storage Conditions	- 20 °C Protected from light
Molecular Weight	600.7
Manufacturer - Research Area	Epigenetics; Cell Signaling / Epigenetics-related Enzymes; Enzyme Substrates & Inhibitors
Description	This novel fluorogenic substrate of HDACs was synthesized with an epsilon-acetylated lysyl moiety and an adjacent MCA moiety at the C-terminus of the peptide chain. The assay utilizing this substrate provides a good tool to characterize the HDAC activity. HDACs are important enzymes for the transcriptional regulation of gene expression.
Absorbtion (nm)	354
Emission (nm)	442
Sequence One-Letter Code	Ac-RGK(Ac)-AMC
Detection Method	Fluorescent
Feature	Fluorogenic substrates
Post Synthesis Coupling	No
Usage	Research use
UNSPSC	12352202
GTIN	5400535150587

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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AS-61855-safety-datasheet.pdf