« Back
Home /
Pannexin-1 (Panx1), Mimetic Blocking Peptide - 1 mg

Pannexin-1 (Panx1), Mimetic Blocking Peptide - 1 mg

Item no.	AS-61911
Manufacturer	AnaSpec
Amount	1 mg
Category	Oncology Neuroscience Neuroinflammation By Cell Type Carcinoma Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Conjugate/Tag	Unconjugated
Purity	Peak Area by HPLC ≥95%
Sequence	H-Trp-Arg-Gln-Ala-Ala-Phe-Val-Asp-Ser-Tyr-OH
Citations	Pelegrin, P. et al. EMBO. J. 25, 5071 (2006); Pelegrin, P. et al.t J. Biol. Chem. 282, 2386 (2007).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	WRQAAFVDSY
Shipping Condition	Room temperature
Available
Manufacturer - Type	Catalog
Manufacturer - Category	Peptides
Manufacturer - Targets	Pannexin
Shipping Temperature	RT
Storage Conditions	- 20 °C
Molecular Weight	1242.4
Description	This is a Pannexin-1 (Panx1) mimetic blocking peptide. Pannexin-1 is a recently identified membrane protein that can form gap junction-like connections allowing intercellular passage of dyes when overexpressed in two adjacent oocytes or mammalian epithelial cell lines. Blockade of pannexin-1 in macrophage endogenously expressing the ATP-gated P2X7 receptor (P2X7R) blocks the initial dye uptake, but not the ionic current, and also blocks processing and release of interleukin-1? (IL-1?) in response to P2X7R activation.
Product Group	LB1A1Z
Research Area	Cell Signaling / Lyophilized
Sequence One-Letter Code	WRQAAFVDSY
GTIN	5400535150525
Usage	Research use
UNSPSC	12352202

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

AS-61911-safety-datasheet.pdf