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Amylin (22-27) [NMeG24, NMeI26], human (IAPP)

Amylin (22-27) [NMeG24, NMeI26], human (IAPP)

Item no.	AS-61937
Manufacturer	AnaSpec
Amount	1 mg
Category	Oncology Neuroscience Molecular Targets for Neuroscience Peptides & Proteins Peptides By Organ Breast Cancer
Type	Peptides
Format	Lyophilized
Specific against	other
Conjugate/Tag	Unconjugated
Purity	Peak Area by HPLC ≥95%
Sequence	H-Asn-Phe-(NMe-Gly)-Ala-(NMe-Ile)-Leu-OH
Citations	Yan, L. et al. PNAS 103, 2046 (2006), Kapurniotu, A., et al. J. Mol. Biol. 315, 339 (2002), Tatarek-Nossol, M. et al. Cell Press 12, 797 (2005).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	NF-(NMe-G)-A-(NMe-I)-L
Shipping Condition	Room temperature
Available
Manufacturer - Category	Catalog Peptides / Catalog Peptides Gr / Peptides
Manufacturer - Targets	Amylin, Islet Amyloid Polypeptide (IAPP)
Shipping Temperature	RT
Storage Conditions	- 20 °C
Molecular Weight	661.8
Manufacturer - Research Area	Diabetes/Metabolism; Hormones; Cell Signaling / Insulin/Amylin; Pancreas; GPCR
Description	This amino acids 22 to 27 fragment is a modification of the human islet amyloid polypeptide hIAPP (NFGAIL) with N-methylation of the amide bonds at G24 and I26. The introduction of two N-methyl rests in the amyloid-core-containing sequence NFGAIL converts this amyloidogenic and cytotoxic sequence into non-amyloidogenic and non-cytotoxic peptide. The peptide is able to bind with high-affinity full-length hIAPP and to inhibit its fibrillogenesis.
Sequence One-Letter Code	NF-(NMe-G)-A-(NMe-I)-L
Post Synthesis Coupling	No
Usage	Research use
UNSPSC	12352202
GTIN	5400535150396

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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AS-61937-safety-datasheet.pdf