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Renin FRET Substrate, R-E(EDANS)--K(Dabcyl)

Renin FRET Substrate, R-E(EDANS)--K(Dabcyl)

Item no.	AS-62022
Manufacturer	AnaSpec
CASRN	791068-69-4
Amount	1 mg
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Purity	Peak Area by HPLC ≥95%
Sequence	H-Arg-Glu(EDANS)-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(DABCYL)-Arg-OH
Citations	Crowley, S. et al. J. Clin. Invest. 115, 1092 (2005); Holzman, T. et al. J. Protein Chem. 9, 663 (1990).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	R-E(EDANS)-IHPFHLVIHT-K(DABCYL)-R
Shipping Condition	Room temperature
Available
Manufacturer - Applications	FRET; Protease activity
Manufacturer - Category	Catalog Peptides / Catalog Peptides Gr / Peptides / Labeling & detection / Blue (<500 nm)
Manufacturer - Targets	Renin
Manufacturer - Conjugate / Tag	Double dyes: EDANS-DABCYL
Shipping Temperature	RT
Storage Conditions	- 20 °C Protected from light
Molecular Weight	2282.8
Manufacturer - Research Area	Cardiovascular Research; Cell Signaling / Renin/Angiotensin (RAS) Cascade; Enzyme Substrates & Inhibitors
Description	This peptide is a renin substrate (angiotensinogen) labeled with EDANS/ DABCYL FRET pair for renin activity studies. The renin-angiotensin system (RAS), acting through type 1 angiotensin (AT1) receptors, is a master regulator of fluid homeostasis.
Absorbtion (nm)	340
Emission (nm)	490
Sequence One-Letter Code	R-E(EDANS)-IHPFHLVIHT-K(DABCYL)-R
Detection Method	Fluorescent
Feature	FRET Substrates
Post Synthesis Coupling	No
Usage	Research use
UNSPSC	12352202
GTIN	5400535150136

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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AS-62022-safety-datasheet.pdf