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Plasmepsin II FRET Substrate, Hemoglobin Fragment, 2837b

Plasmepsin II FRET Substrate, Hemoglobin Fragment, 2837b

Item no.	AS-62050
Manufacturer	AnaSpec
Amount	1 mg
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Conjugate/Tag	Unconjugated
Purity	Peak Area by HPLC ≥95%
Sequence	EDANS-CO-CH2-CH2-CO-Ala-Leu-Glu-Arg-Met-Phe-Leu-Ser-Phe-Pro-Dap(DABCYL)-OH
Citations	Istvan, E. and D. Goldberg. J. Biol. Chem. 280, 6890 (2005); Liu, J. et al. J. Biol. Chem. 281, 38682 (2006).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	EDANS-CO-CH2-CH2-CO-ALERMFLSFP-Dap(DABCYL)OH
Shipping Condition	Room temperature
Available
Manufacturer - Applications	FRET; Protease activity
Manufacturer - Category	Catalog Peptides / Catalog Peptides Gr / Peptides / Labeling & detection / Blue (<500 nm)
Manufacturer - Targets	Plasmepsin
Manufacturer - Conjugate / Tag	Double dyes: EDANS-DABCYL
Shipping Temperature	RT
Storage Conditions	- 20 °C Protected from light
Molecular Weight	1896.2
Manufacturer - Research Area	Immunology and Infectious disease; Cell Signaling / Microbiology/Bacteriology; Enzyme Substrates & Inhibitors
Description	The sequence of this synthetic peptide is based on the primary site of cleavage by plasmepsin II (PM II) within hemoglobin (Hb), and numbering of the peptide corresponds to the residue within the ?-chain of Hb. Plasmepsins are involved in the early steps of hemoglobin degradation. They are able to recognize intact hemoglobin and make an initial cleavage in the B helix of the hemoglobin ?-chain between Phe-33 and Leu-34.
Absorbtion (nm)	340
Emission (nm)	490
Sequence One-Letter Code	EDANS-CO-CH2-CH2-CO-ALERMFLSFP-Dap(DABCYL)OH
Detection Method	Fluorescent
Feature	FRET Substrates
Post Synthesis Coupling	No
Usage	Research use
UNSPSC	12352202
GTIN	5400535150051

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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AS-62050-safety-datasheet.pdf