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Plasmepsin II FRET Substrate, Hemoglobin Fragment, 2837b - 1 mg

Plasmepsin II FRET Substrate, Hemoglobin Fragment, 2837b - 1 mg

Item no.	AS-62050
Manufacturer	AnaSpec
Amount	1 mg
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Conjugate/Tag	Unconjugated
Purity	Peak Area by HPLC ≥95%
Sequence	EDANS-CO-CH2-CH2-CO-Ala-Leu-Glu-Arg-Met-Phe-Leu-Ser-Phe-Pro-Dap(DABCYL)-OH
Citations	Istvan, E. and D. Goldberg. J. Biol. Chem. 280, 6890 (2005); Liu, J. et al. J. Biol. Chem. 281, 38682 (2006).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	EDANS-CO-CH2-CH2-CO-ALERMFLSFP-Dap(DABCYL)OH
Shipping Condition	Room temperature
Available
Manufacturer - Type	Catalog
Manufacturer - Applications	FRET; Protease activity
Manufacturer - Category	Peptides
Manufacturer - Targets	Plasmepsin
Manufacturer - Conjugate / Tag	EDANS-DABCYL
Shipping Temperature	RT
Storage Conditions	- 20 °C Protected from light
Molecular Weight	1896.2
Description	The sequence of this synthetic peptide is based on the primary site of cleavage by plasmepsin II (PM II) within hemoglobin (Hb), and numbering of the peptide corresponds to the residue within the alpha-chain of Hb. Plasmepsins are involved in the early steps of hemoglobin degradation. They are able to recognize intact hemoglobin and make an initial cleavage in the B helix of the hemoglobin alpha-chain between Phe-33 and Leu-34.
Product Group	LB1A1Z
Research Area	Immunology and Infectious disease; Cell Signaling / Lyophilized
Absorbtion (nm)	340
Emission (nm)	490
Sequence One-Letter Code	EDANS-CO-CH2-CH2-CO-ALERMFLSFP-Dap(DABCYL)OH
GTIN	5400535150051
Detection Method	Fluorescent
Usage	Research use
UNSPSC	12352202

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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AS-62050-safety-datasheet.pdf