epsilon-V1-2, PKCe Inhibitor

Catalog Peptides / Catalog Peptides Gr / Peptides

RT

844

This peptide is derived from residues 14-21 of protein kinase C C2 (?PKC C2). This peptide specifically inhibits ?PKC by disrupting PKC binding to its receptor, RACK2. ?PKC mediated signal transduction plays a role in cell proliferation, differentiation, and apoptosis.
- Pyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic ?-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.

No

12352202