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Bacterial Sortase Substrate I, FRET - 1 mg

Bacterial Sortase Substrate I, FRET - 1 mg

Item no.	AS-62231
Manufacturer	AnaSpec
Amount	1 mg
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Conjugate/Tag	Biotin
Purity	Peak Area by HPLC ≥95%
Sequence	DABCYL-Leu-Pro-Glu-Thr-Gly-EDANS
Citations	Mazmanian, S. et al. PNAS 99, 2293 (2002); Ilangovan, U. et al. PNAS 98, 6056 (2001), Ton-That, H. et al. PNAS 96, 12424 (1999); W. Navarre and O. Schneewind Microbiol. Mol. Biol. Rev. 63, 174 (1999).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	DABCYL-LPETG-EDANS
Shipping Condition	Room temperature
Available
Manufacturer - Type	Catalog
Manufacturer - Applications	FRET; Protease activity
Manufacturer - Category	Peptides
Manufacturer - Targets	Sortase A
Manufacturer - Conjugate / Tag	EDANS-DABCYL
Shipping Temperature	RT
Storage Conditions	- 20 °C Protected from light
Molecular Weight	1015.2
Description	This 5-amino acid peptide is a sortase substrate, C-terminal sorting signal. Sortase cleaves surface proteins at the LPXTG motif and catalyzes the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Sortases are a family of Gram-positive transpeptidases responsible for anchoring surface protein virulence factors to the peptidoglycan cell wall layer. Cleavage of this FRET substrate by sortase reveals the fluorescent signal, Abs/Em = 340/490 nm.
Product Group	LB1A3Z
Research Area	Immunology and Infectious disease; Cell Signaling / Lyophilized
Absorbtion (nm)	340
Emission (nm)	490
Sequence One-Letter Code	DABCYL-LPETG-EDANS
GTIN	5400535149543
Detection Method	Fluorescent
Usage	Research use
UNSPSC	12352202

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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AS-62231-safety-datasheet.pdf