Histone H4 (1-7), N-Terminal - 1 mg

Catalog

Histone H4 Fragment; Histone

- 20 °C

This is amino acids 1 to 7 fragment of the histone H3. Alterations in chromatin structure, such as nucleosome sliding, removal of nucleosomes, and disruption of DNA-histone or histone-histone contacts through post-translational modification of the histones, have been linked to transcriptional regulation, DNA damage repair, and replication, among other cellular processes. Modification of histones occurs primarily in the N-terminal residues or tail region. These modifications include phosphorylation, ubiquitinylation, methylation, sumolyation, and acetylation. Lys5 may serve as the acetylation site for this peptide.

Epigenetics / Lyophilized

5400535148126

12352202