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gp91 ds-tat, NADPH oxidase inhibitor

gp91 ds-tat, NADPH oxidase inhibitor

Item no.	AS-63818
Manufacturer	AnaSpec
Amount	1 mg
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Conjugate/Tag	Unconjugated
Purity	Peak Area by HPLC ≥95%
Sequence	H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Cys-Ser-Thr-Arg-Ile-Arg-Arg-Gln-Leu-NH2
Citations	Park, L. J. Neuroscience 25, 1769 (2005); Park, L. et al. Proc. Natl. Acad. Sci. 105, 1347 (2008)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	YGRKKRRQRRRCSTRIRRQL-NH2
Shipping Condition	Room temperature
Available
Manufacturer - Applications	Enzyme activity
Manufacturer - Category	Catalog Peptides / Catalog Peptides Gr / Peptides
Manufacturer - Targets	NADP, NADPH
Shipping Temperature	RT
Storage Conditions	- 20 °C
Molecular Weight	2673.3
Manufacturer - Research Area	Cell Signaling; Cell & Tissue Biology / Enzyme Substrates & Inhibitors; Oxidative Stress
Description	In the kidney, there are many enzymatic systems that contribute to the production of Reactive Oxygen Species, including nicotinamide adenine dinucleotide phosphate (NADPH) oxidase. NADPH oxidase has been considered as the major source of superoxide in the kidney, and its action relies on an enzymatic complex with five subunits, including gp91phox. This peptide is composed of gp91phox sequence linked to the human immunodeficiency virus-tat peptide. The tat sequence facilitates the entry of this peptide into all cells. It is used as a peptide inhibitor for NADPH oxidase assembly.
Sequence One-Letter Code	YGRKKRRQRRRCSTRIRRQL-NH2
Post Synthesis Coupling	No
Usage	Research use
UNSPSC	12352202
GTIN	5400535146672

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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AS-63818-safety-datasheet.pdf