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[Lys(Ac)9]-Histone H3 (1-24) - 1 mg

[Lys(Ac)9]-Histone H3 (1-24) - 1 mg

Item no.	AS-64453
Manufacturer	AnaSpec
Amount	1 mg
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Purity	Peak Area by HPLC ≥95%
Sequence	H-Ala-Arg-Thr-Lys-Gln-Thr-Ala-Arg-Lys(Ac)-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-Lys-Gln-Leu-Ala-Thr-Lys-Ala-OH
Citations	Kitange GJ. et al. Clin Can Res. 18:4070 (2012)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	ARTKQTAR-K(Ac)-STGGKAPRKQLATKA
Shipping Condition	Room temperature
Available
Manufacturer - Type	Catalog
Manufacturer - Category	Peptides
Manufacturer - Targets	Histone H3 Fragment; Histone
Shipping Temperature	RT
Storage Conditions	- 20 °C
Molecular Weight	2597.2
Description	This Histone 3 peptide is acetylated at lysine residue at 9th position. In a glioblastoma xenograft expressing a O6-methylguanine-DNA methyltransferase (MGMT), increased H3K9-ac was observed in correlation to histone acetylation and MGMT upregulation, thus demonstrating a mechanism driven by chromatin-mediated MGMT upregulation in potentially directing epigenetic therapies to influence the mechanisms of resistance development in glioblastomas.
Product Group	LB1A1Z
Research Area	Epigenetics / Lyophilized
Sequence One-Letter Code	ARTKQTAR-K(Ac)-STGGKAPRKQLATKA
GTIN	5400535144289
Usage	Research use
UNSPSC	12352202

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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AS-64453-safety-datasheet.pdf