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Angiotensin II, human, ClearPoint™ Ile labeled (13C and 15N)

Angiotensin II, human, ClearPoint™ Ile labeled (13C and 15N)

Item no.	AS-64805
Manufacturer	AnaSpec
Amount	0.1 mg
Category	Peptides & Proteins Cardiovascular Research Heart Failure Myocardial Infarction Hypertension Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Conjugate/Tag	Unconjugated
Purity	Peak Area by HPLC ≥95%
Sequence	H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH [Ile= Ile(U13C6,15N)]
Citations	Cobb, C. et al. Gen Comp Endocrinol 127, 8 (2002); Lundequist, A. et al.J Bio Chem 279, 32339 (2004); Kinoshita, A. et al. J Biol Chem 266, 19192 (1991); Spyroulias, G. et al. Eur J Biochem 270, 21
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	DRVY-I-HPF [I= I(U13C6,15N)]
Shipping Condition	Room temperature
Available
Manufacturer - Applications	Mass Spectrometry
Manufacturer - Category	Catalog Peptides / Catalog Peptides Gr / Peptides
Manufacturer - Targets	Angiotensin
Shipping Temperature	RT
Storage Conditions	- 20 °C
Molecular Weight	1053.2
Manufacturer - Research Area	Cardiovascular Research; Cell Signaling / Renin/Angiotensin (RAS) Cascade; GPCR
Description	This peptide is angiontensin II (Ang II) with Isoleucine universally labeled with 13C and 15N. The octapeptide angiotensin II (Ang II) exerts a wide range of effects on the cardiovascular system. It is also implicated in the regulation of cell proliferation, fibrosis and apoptosis. Ang II is formed through cleavage of Ang I by the angiotensin-converting enzyme (ACE) or chymases. Human heart chymase, a chymotrypsin-like serine proteinase, hydrolyzes the Phe8-His9 bond to yield the octapeptide hormone angiotensin II and His-Leu.
Sequence One-Letter Code	DRVY-I-HPF [I= I(U13C6, 15N)]
Post Synthesis Coupling	No
Usage	Research use
UNSPSC	12352202
GTIN	5400535142605

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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AS-64805-safety-datasheet.pdf