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Protease-Activated Receptor-2, PAR-2 Agonist, amide

Protease-Activated Receptor-2, PAR-2 Agonist, amide

Item no.	AS-65490
Manufacturer	AnaSpec
CASRN	729589-58-6
Amount	1 mg
Category	Neuroscience Neuroinflammation Peptides & Proteins Cardiovascular Research Thrombosis & Hemostasis Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Conjugate/Tag	Unconjugated
Purity	Peak Area by HPLC ≥95%
Sequence	2-Furoyl-Leu-Ile-Gly-Arg-Leu-Orn-NH2
Citations	McGuire, JJ. et al. J Pharmacol Exp Ther 309, 1124 (2004).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Protease Activated Receptor 2,PAR 2,PAR 2 Agonist Amide
Shipping Condition	Room temperature
Available
Manufacturer - Category	Catalog Peptides / Catalog Peptides Gr / Peptides
Manufacturer - Targets	Protease-Activated Receptor (PAR)
Shipping Temperature	RT
Storage Conditions	- 20 °C
Molecular Weight	778
Manufacturer - Research Area	Cardiovascular Research; Cell Signaling / Coagulation; GPCR
Description	The peptide 2-furoyl-LIGRLO-NH2 showed higher potency and receptor selectivity for in vitro assays than other PAR-2-activating peptides. 2-Furoyl-LIGRLO-NH2 peptide was equally or more potent than SLIGRL-NH2 for increasing intracellular calcium in cultured human and rat PAR-2-expressing cells and significantly more potent than SLIGRL-NH2 in assays of tissue PAR-2 activity.
Sequence One-Letter Code	2-Furoyl-LIGRLO-NH2
Post Synthesis Coupling	No
Usage	Research use
UNSPSC	12352202
GTIN	5400535133962

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AS-65490-safety-datasheet.pdf