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Orexin B, mouse/rat

Orexin B, mouse/rat

Item no.	AS-65574
Manufacturer	AnaSpec
CASRN	202801-92-1
Amount	1 mg
Category	Metabolism Glucose Homeostasis Regulation of Appetite Peptides & Proteins Obesity Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Conjugate/Tag	Unconjugated
Purity	Peak Area by HPLC ≥95%
Sequence	Arg-Pro-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Asn-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2
Citations	1. Martynska L., et.al., Neuroendocr Lett 4(26), 289-292 (2005). 2. Ebrahim I.O., et.al., J of Royl Soc of Med95, 227-230 (2002). 3. Chiou L-C., et.al., Cur Pharm Des16(28), 3089-3100 (2010).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Orexin peptide,Orexin,hypothalamic peptide
Shipping Condition	Room temperature
Available
Manufacturer - Category	Catalog Peptides / Catalog Peptides Gr / Peptides
Manufacturer - Targets	Orexin
Shipping Temperature	RT
Storage Conditions	- 20 °C
Molecular Weight	2936.6
Manufacturer - Research Area	Neuroscience; Cell Signaling / Neuropeptides; GPCR
Description	Orexins are synthesized by posterolateral neurons in hypothalamus. They bind to orexin-1 (OxR1) and orexin 2 (OxR2) receptors. Orexin A can bind to both OxR1 and OxR2 while Orexin B can associate with OxR2 only. Both Orexins are involved in the regulation of arousal and sleep states, energy homeostasis, and autonomic central control.
Sequence One-Letter Code	RPGPPGLQGRLQRLLQANGNHAAGILTM-NH2
Post Synthesis Coupling	No
Usage	Research use
UNSPSC	12352202
GTIN	5400535160944

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AS-65574-safety-datasheet.pdf