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Caspase 3 (Apopain) Substrate 1r-z, fluorogenic - 5 mg

Item no. AS-60304-5
Manufacturer AnaSpec
Amount 5 mg
Category
Type Fluorescent dyes and probes
Format Lyophilized
Specific against other
Conjugate/Tag Unconjugated
Purity Peak Area by HPLC ≥95%
Sequence z-(Asp-Glu-Val-Asp)2-Rh110
Citations Gurtu V, et al. (1997). Fluorometric and colorimetric detection of caspase activity associated with apoptosis. Anal Biochem 251, 98-102; Martins LM, et al. (1997). Activation of multiple interleukin-1 ? converting enzyme homologues in cytosol and nuclei of HL-60 cells during etoposide-induced apoptosis. J Biol Chem 272, 7421-30.
ECLASS 10.1 30196090
ECLASS 11.0 30196090
UNSPSC 12000000
Alias (Z-DEVD)2-Rh110
Shipping Condition Room temperature
Available
Manufacturer - Type
Catalog
Manufacturer - Applications
FRET; Protease activity
Manufacturer - Category
Peptides
Manufacturer - Targets
Caspase; Caspase 3
Shipping Temperature
RT
Storage Conditions
- 20 °C Protected from light
Molecular Weight
1515.5
Description
Rh110 (rhodamine 110)-derived caspase substrates are probably the most sensitive indicators widely used for the fluorimetric detection of various caspase activities. Cleavage of Rh110 peptides by caspases generates strongly fluorescent Rh110 that is monitored fluorimetrically at 510-530 nm with excitation of 488 nm, the most common excitation light source used in fluorescence instruments.
Product Group
LB1A3Z
Research Area
Cancer & Apoptosis; Cell Signaling / Lyophilized
Absorbtion (nm)
488
Emission (nm)
520
Sequence One-Letter Code
(Z-DEVD)2-Rh110
GTIN
5400535158538
Detection Method
Fluorescent
Usage
Research use
UNSPSC
12352202

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 5 mg
Available: In stock
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