Comparison

Anti-Nav1.7 Na+ Channel Antibody

Item no. 75-103-020
Manufacturer Antibodies Incorporated
Amount 20 uL
Category
Format Liquid
Applications WB, IP, IHC, ICC
Clone N68/6
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG1
Conjugate/Tag Unconjugated
Alias Sodium channel protein type 9 subunit alpha (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1) (PN1) (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7)
Shipping Condition Cool pack
Available
Manufacturer - Type
Primary Antibody
Manufacturer - Targets
Nav1.7 Na+ channel
Country of Origin
United States
Shipping Temperature
Shipped on ice packs
Storage Conditions
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight
230 kDa
Manufacturer - Research Area
Ion Channels and Modulators, Na+ Channels
Expiration
24 months from date of receipt
Immunogen
Fusion protein amino acids 1751-1946 (cytoplasmic C-terminus) of human Nav1.7 (accession number Q15858) produced recombinantly in E. Coli
Immunogen Species
Human
Description
Our Anti-Nav1.7 Na+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N68/6. It detects human, mouse, and rat Nav1.7 Na+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.
Target Description
Nav1.7 subunit alpha, or SCN9A, is a member of the voltage gated sodium channel family. It is expressed at the terminal ends of sensory neurons in the dorsal root ganglion (DRG) and in trigeminal and sympathetic ganglion neurons. A major function of Nav1.7 is the generation and conduction of action potentials in nociceptors, or “pain receptors” and thus involved in pain sensation. Changes in Nav1.7 expression have been linked to primary erythermalgia, primary erythermalgia, and Congenital insensitivity to pain
Clonality
Monoclonal
Manufacturer - Specificity
No cross-reactivity against other Nav channels
Concentration
1 mg/mL
Form
Purified by Protein A chromatography
Buffer
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.31
Production Notes
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Quality Control
Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
Quality Control: Application
ICC
Dilution Range: WB
1:500
Dilution Range: IHC
1:250
Dilution Range: ICC
1:250
Usage Statement
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement
We produce our Nav1.7 Na+ channel mouse monoclonal primary antibody from hybridoma clone N68/6. It is great in IHC, ICC, IP, WB and is purified by Protein A chromatography.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 20 uL
Available: In stock
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