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GPR31 Antibody (Extracellular Domain)

GPR31 Antibody (Extracellular Domain)

Item no.	ABC-ALS10283
Manufacturer	Abcepta
Amount	50 ug
Category	Metabolism Cholesterol & Lipid Metabolism Antibodies Immunohistochemistry Enzymes Primary Antibodies Leukotriene Metabolism
Type	Antibody Primary
Applications	IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Citations	Zingoni A.,et al.Genomics 42:519-523(1997). Kaighin V.A.,et al.Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases. Mungall A.J.,et al.Nature 425:805-811(2003). Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. Guo Y.,et al.J. Biol. Chem. 286:33832-33840(2011).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor,12-(S)-HETE receptor,12-HETER,G-protein coupled receptor 31,GPR31
Similar products	GPR31, 10, 8, 14-eicosatetraenoic acid receptor, 12-HETER, 12-(S)-HETE receptor, G-protein coupled receptor 31, 12-(S)-hydroxy-5
Available
Manufacturer - Targets	Human GPR31. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Storage Conditions	Long term: -70°C; Short term: +4°C
Bio Background	High-affinity receptor for 12-(S)-hydroxy-5, 8, 10, 14- eicosatetraenoic acid (12-S-HETE). 12-(S)-HETE is an arachidonic acid metabolite secreted by platelets and tumor cells, and known to induce endothelial cells retraction allowing invasive cell access to the subendothelial matrix, which is a critical step for extravasation or metastasis. Ligand-binding lead to activation of ERK1/2 (MAPK3/MAPK1), MEK, and NF-kappa-B.
Clonality	Polyclonal
Gene Name	GPR31
Subtitle	Rabbit Polyclonal Antibody
Reactivity	H
Calculated Molecular Weight	35075
Purification	Immunoaffinity purified
Concentration	1 mg/ml
Dilution	IHC-P (2-4 µg/ml)
Antigen Type	Synthetic peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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