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CD95 / FAS Antibody (clone LT95)

CD95 / FAS Antibody (clone LT95)

Item no.	ABC-ALS12492
Manufacturer	Abcepta
Amount	50 ug
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Signaling Antibodies By Cell Type Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis Flow Cytometry Immunohistochemistry Primary Antibodies
Type	Antibody Monoclonal
Applications	FC, IHC-P
Clone	LT95
Specific against	Human (Homo sapiens)
Host	Mouse
Citations	Itoh N.,et al.Cell 66:233-243(1991). Oehm A.,et al.J. Biol. Chem. 267:10709-10715(1992). Liu C.,et al.Biochem. J. 310:957-963(1995). Cascino I.,et al.J. Immunol. 154:2706-2713(1995). Cascino I.,et al.J. Immunol. 156:13-17(1996).
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Tumor necrosis factor receptor superfamily member 6,Apo-1 antigen,Apoptosis-mediating surface antigen FAS,FASLG receptor,CD95,FAS,APT1,FAS1,TNFRSF6
Similar products	FAS, TNFRSF6, APT1, FAS1, Tumor necrosis factor receptor superfamily member 6, Apo-1 antigen, Apoptosis-mediating surface antigen FAS, FASLG receptor, CD95
Available
Manufacturer - Targets	Reacts with CD95 (Fas/APO-1), a 46 kD single chain type I glycoprotein of the tumor necrosis factor/nerve growth factor (TNF/NGF) receptor superfamily, expressed on a variety of normal and neoplastic cells. It seems that the antibody LT95 does not in..
Storage Conditions	+4°C or -20°C, Avoid repeated freezing and thawing.
Bio Background	Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death- inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS- mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
Clonality	Monoclonal
Gene Name	FAS
Subtitle	Mouse Monoclonal Antibody
Reactivity	H
Calculated Molecular Weight	37732
Purification	Ion exchange chromatography
Concentration	1 mg/ml
Dilution	IHC-P (10 µg/ml)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 1/1/2026

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