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F12 / Factor XII Antibody

F12 / Factor XII Antibody

Item no.	ABC-ALS12632
Manufacturer	Abcepta
Amount	50 ug
Category	Neuroscience Molecular Targets for Neuroscience Antibodies Cell Biology Cell Status Apoptosis Immunohistochemistry Immunoprecipitation ELISA Primary Antibodies Immunostaining
Type	Antibody Primary
Applications	IP, ELISA, IHC-P
Specific against	Human (Homo sapiens)
Host	Caprine
Citations	Cool D.E.,et al.J. Biol. Chem. 262:13662-13673(1987). Schmutz J.,et al.Nature 431:268-274(2004). Tripodi M.,et al.Nucleic Acids Res. 14:3146-3146(1986). Cool D.E.,et al.J. Biol. Chem. 260:13666-13676(1985). Que B.G.,et al.Biochemistry 25:1525-1528(1986).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Coagulation factor XII,3.4.21.38,Hageman factor,HAF,Coagulation factor XIIa heavy chain,Beta-factor XIIa part 1,Beta-factor XIIa part 2,Coagulation factor XIIa light chain,F12
Similar products	F12, Coagulation factor XII, Hageman factor, Coagulation factor XIIa heavy chain, Beta-factor XIIa part 1, Beta-factor XIIa part 2, Coagulation factor XIIa light chain, HAF, 3.4.21.38
Available
Manufacturer - Applications	IHC-P, E, IP, IE
Manufacturer - Targets	Specific for Factor XII as demonstrated by immunodiffusion. A single precipitin arc was obtained with normal plasma and no reaction was observed with F. XII-deficient plasma.
Storage Conditions	Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
Bio Background	Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta- factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa.
Clonality	Polyclonal
Gene Name	F12
Subtitle	Goat Polyclonal Antibody
Reactivity	H
Calculated Molecular Weight	67792
Purification	Ammonium sulfate precipitation
Concentration	1 mg/ml
Dilution	IHC-P (5 µg/ml)
Antigen Type	Purified protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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