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ITGB2 / CD18 Antibody (aa534-546, clone MEM-48)

ITGB2 / CD18 Antibody (aa534-546, clone MEM-48)

Item no.	ABC-ALS12925
Manufacturer	Abcepta
Amount	50 ug
Category	Neuroscience Neuroinflammation Antibodies Cell Biology Cell Movement Cell Adhesion Flow Cytometry Immunohistochemistry Immunoprecipitation Western Blot Primary Antibodies
Type	Antibody Monoclonal
Applications	WB, FC, IP, IHC-P, IHC-F
Clone	MEM-48
Specific against	Human (Homo sapiens)
Host	Mouse
Citations	Kishimoto T.K.,et al.Cell 48:681-690(1987). Weitzman J.B.,et al.FEBS Lett. 294:97-103(1991). Ota T.,et al.Nat. Genet. 36:40-45(2004). Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases. Hattori M.,et al.Nature 405:311-319(2000).
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Integrin beta-2,Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta,Complement receptor C3 subunit beta,CD18,ITGB2,CD18,MFI7
Similar products	ITGB2, CD18, MFI7, Integrin beta-2, Cell surface adhesion glycoproteins LFA-1/CR3/p150, 95 subunit beta, Complement receptor C3 subunit beta
Available
Manufacturer - Applications	WB, IHC-P, IP, IHC-F, FC, FuncS
Manufacturer - Targets	Recognizes an epitope involving residues 534-546 in cysteine-rich repeat 3 of the CD18 antigen (integrin beta2 subunit; beta2 integrin). CD18 is a 90-95 kD type I transmembrane protein expressed on all leukocytes.
Storage Conditions	Store at 2-8°C. Do not freeze.
Bio Background	Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha- D/beta-2 is a receptor for ICAM3 and VCAM1. Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation.
Clonality	Monoclonal
Gene Name	ITGB2
Subtitle	Mouse Monoclonal Antibody
Reactivity	H
Calculated Molecular Weight	84791
Purification	Protein A purified
Concentration	1 mg/ml
Dilution	Flo (2 µg/ml), IHC-P (10 µg/ml), IP (2 µg/ml), WB (2 µg/ml) ,
Antigen Type	Cells

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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