Comparison

STAT3 Antibody (clone 7G3H4)

Item no. ABC-ALS13157
Manufacturer Abcepta
Amount 50 ul
Category
Type Antibody Monoclonal
Applications WB, ELISA, IHC-P
Clone 7G3H4
Specific against Human (Homo sapiens)
Host Mouse
Citations Akira S.,et al.Cell 77:63-71(1994).
Della Pietra L.,et al.Gene 213:119-124(1998).
Feinstein E.,et al.Patent number EP2440214, 18-APR-2012.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Signal transducer and activator of transcription 3,Acute-phase response factor,STAT3,APRF
Similar products STAT3, APRF, Signal transducer and activator of transcription 3, Acute-phase response factor
Available
Manufacturer - Targets
Human STAT3
Storage Conditions
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
Bio Background
Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)- responsive elements identified in the promoters of various acute- phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity).
Clonality
Monoclonal
Gene Name
STAT3 {ECO:0000303|PubMed:9630560, ECO:0000312|HGNC:HGNC:11364}
Subtitle
Mouse Monoclonal Antibody
Reactivity
H
Calculated Molecular Weight
88068
Purification
Ascites
Dilution
IHC-P (1:200), WB (1:500-1:2000),

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ul
Available: In stock
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