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CD95 / FAS Antibody (Internal)

CD95 / FAS Antibody (Internal)

Item no.	ABC-ALS13384
Manufacturer	Abcepta
Amount	50 ug
Category	Antibodies Cell Biology Cell Status Apoptosis Immunohistochemistry Western Blot ELISA Primary Antibodies Immunostaining
Type	Antibody Primary
Applications	WB, ELISA, IHC-P
Specific against	Human (Homo sapiens)
Host	Caprine
Citations	Itoh N.,et al.Cell 66:233-243(1991). Oehm A.,et al.J. Biol. Chem. 267:10709-10715(1992). Liu C.,et al.Biochem. J. 310:957-963(1995). Cascino I.,et al.J. Immunol. 154:2706-2713(1995). Cascino I.,et al.J. Immunol. 156:13-17(1996).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Tumor necrosis factor receptor superfamily member 6,Apo-1 antigen,Apoptosis-mediating surface antigen FAS,FASLG receptor,CD95,FAS,APT1,FAS1,TNFRSF6
Similar products	FAS, TNFRSF6, APT1, FAS1, Tumor necrosis factor receptor superfamily member 6, Apo-1 antigen, Apoptosis-mediating surface antigen FAS, FASLG receptor, CD95
Available
Manufacturer - Targets	Human FAS / CD95. This antibody is expected to recognize reported isoforms 1 (NP_000034.1), 2 (NP_690610.1) and 3 (NP_690611.1).
Storage Conditions	Store at -20°C. Minimize freezing and thawing.
Bio Background	Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death- inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS- mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
Clonality	Polyclonal
Gene Name	FAS
Subtitle	Goat Polyclonal Antibody
Reactivity	H
Calculated Molecular Weight	37732
Purification	Immunoaffinity purified
Concentration	0.5 mg/ml
Dilution	ELISA (1:32000), IHC-P (3.75 µg/ml), WB (0.1-0.3 µg/ml)
Antigen Type	Synthetic peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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