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TLR3 Antibody

TLR3 Antibody

Item no.	ABC-ALS13663
Manufacturer	Abcepta
Amount	50 ul
Category	Neuroscience Neural Lineage Markers Antibodies Cell Biology Cell Status Cell Metabolism Immunohistochemistry Western Blot Immunofluorescence Immunocytochemistry Oxidative Stress Primary Antibodies Immunochemistry
Type	Antibody Primary
Applications	WB, IF, ICC, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Citations	Rock F.L.,et al.Proc. Natl. Acad. Sci. U.S.A. 95:588-593(1998). Lafon M.,et al.J. Mol. Neurosci. 29:185-194(2006). Nakajima T.,et al.Immunogenetics 60:727-735(2008). Macquin C.,et al.Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases. Ota T.,et al.Nat. Genet. 36:40-45(2004).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Toll-like receptor 3,CD283,TLR3
Similar products	TLR3, Toll-like receptor 3, CD283
Available
Manufacturer - Targets	Human TLR3. Predicted cross-reactivity based on amino acid sequence homology: mouse (81%), guinea pig (84%), rat (83%), rabbit (82%), bovine (86%), cat (86%), pig (84%), monkey (96%).
Storage Conditions	Aliquot and store at -20°C. Minimize freezing and thawing.
Bio Background	Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response.
Clonality	Polyclonal
Gene Name	TLR3
Subtitle	Rabbit Polyclonal Antibody
Reactivity	H
Calculated Molecular Weight	103829
Purification	Immunoaffinity purified
Concentration	1 mg/ml
Dilution	IF (1:100-1:200), IHC-P (10 µg/ml), WB (1:1000-1:10000)
Antigen Type	Recombinant protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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