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ABRI / ITM2B Antibody (Internal)

ABRI / ITM2B Antibody (Internal)

Item no.	ABC-ALS14582
Manufacturer	Abcepta
Amount	50 ug
Category	Neuroscience Aging & Neurological Disorders Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies Immunostaining
Type	Antibody Primary
Applications	WB, ELISA, IHC-P
Specific against	Human (Homo sapiens), Monkey (Cynomolgus, Simian), Cattle (Bovine)
Host	Caprine
Citations	Vidal R.,et al.Nature 399:776-781(1999). Vidal R.,et al.Proc. Natl. Acad. Sci. U.S.A. 97:4920-4925(2000). Ren S.,et al.Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases. Hu R.-M.,et al.Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000). Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	soluble form, membrane form, ITM2B, BRI, BRI2, Integral membrane protein 2B, Immature BRI2, Protein E25B, Transmembrane protein BRI, Mature BRI2, BRI2 intracellular domain, BRI2C, Bri23 peptide, ABri23, C-terminal peptide, P23 peptide, imBRI2, Bri, mBRI2, BRI2 ICD, Bri2-23
Available
Manufacturer - Targets	Human ITM2B.
Storage Conditions	Store at -20°C. Minimize freezing and thawing.
Bio Background	Plays a regulatory role in the processing of the beta- amyloid A4 precursor protein (APP) and acts as an inhibitor of the beta-amyloid peptide aggregation and fibrils deposition. Plays a role in the induction of neurite outgrowth. Functions as a protease inhibitor by blocking access of secretases to APP cleavage sites. Bri23 peptide prevents aggregation of APP beta-amyloid protein 42 peptide into toxic oligomers.
Clonality	Polyclonal
Gene Name	ITM2B
Subtitle	Goat Polyclonal Antibody
Reactivity	H, Pr, Hs, B
Calculated Molecular Weight	30338
Purification	Immunoaffinity purified
Concentration	0.5 mg/ml
Dilution	ELISA (1:8000), IHC-P (2.5-3.75 µg/ml), WB (1-3 µg/ml)
Antigen Type	Synthetic peptide
Manufacturer - Alias	Integral membrane protein 2B, Immature BRI2, imBRI2, Protein E25B, Transmembrane protein BRI, Bri, BRI2, membrane form, Mature BRI2, mBRI2, BRI2 intracellular domain, BRI2 ICD, BRI2C, soluble form, Bri23 peptide, Bri2-23, ABri23, C-terminal peptide, P23 peptide, ITM2B, BRI, BRI2
Manufacturer - Similar	Integral membrane protein 2B, Immature BRI2, imBRI2, Protein E25B, Transmembrane protein BRI, Bri, BRI2, membrane form, Mature BRI2, mBRI2, BRI2 intracellular domain, BRI2 ICD, BRI2C, soluble form, Bri23 peptide, Bri2-23, ABri23, C-terminal peptide, P23 peptide, ITM2B, BRI, BRI2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 3/5/2026

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