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NR3C1 Antibody

NR3C1 Antibody

Item no.	ABC-AM2187b
Manufacturer	Abcepta
Amount	400 ul
Category	Oncology Antibodies By Cell Type Carcinoma Western Blot Primary Antibodies
Type	Antibody Monoclonal
Applications	WB
Clone	740CT12.1.5
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Mouse
Isotype	IgM Kappa
Citations	Hollenberg S.M., et al. Nature 318:635-641(1985). Encio I.J., et al. J. Biol. Chem. 266:7182-7188(1991). Wang W., et al. Nucleic Acids Res. 39:44-58(2011). Turner J.D., et al. Ann. N. Y. Acad. Sci. 1095:334-341(2007). Munroe D.G., et al. Submitted (SEP-1993) to the EMBL/GenBank/DDBJ databases.
NCBI	NP_000167.1,NP_001018084.1,NP_001018085.1,NP_001018086.1,NP_001018087.1,NP_001018661.1,NP_001019265.1,NP_001191187.1,NP_001191188.1,NP_001191189.1,NP_001191190.1,NP_001191191.1,NP_001191192.1,NP_00119
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Glucocorticoid receptor,GR,Nuclear receptor subfamily 3 group C member 1,NR3C1,GRL
Available
Manufacturer - Category	Crown Antibodies; Primary Antibodies; Cancer; Signal Transduction; Mitochondrion
Manufacturer - Targets	This NR3C1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 136-164 amino acids from human NR3C1.
Bio Background	Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE) and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. Plays a significant role in transactivation. Involved in nuclear translocation (By similarity).
Clonality	Monoclonal
Gene Name	NR3C1
Subtitle	Mouse Monoclonal Antibody (Mab)
Reactivity	H, M
Calculated Molecular Weight	85659
Antigen Region	136-164
Formulation	Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
Dilution	WB: 1:1000
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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