Anti-SOX2 Antibody

Item no.	ABC-AN1557
Manufacturer	Abcepta
Amount	100 ul
Category	Oncology Neuroscience Neural Lineage Markers Antibodies By Cell Type Carcinoma Western Blot Primary Antibodies Calcium Binding Protein Markers Interneuron Markers
Type	Antibody Primary
Applications	WB
Specific against	other
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	SRY box 2,sex-determining region Y box 2
Available
Manufacturer - Category	Primary Antibodies; Developmental Biology; Neuroscience; Stem Cells
Manufacturer - Targets	SOX2 (SRY (sex-determining region Y)-box 2) is one of 20 members of the Sox family proteins that play essential roles in cell differentiation, development, and organogenesis. SOX2, a group B Sox family protein, is one of the master transcriptional factors, along with Oct3/4 (Nichols, J., et al, 1998) and PAK6 (Kamachi, Y. et al, 2001) that are important in maintaining the pluripotency of embryonic stem cells, thus making SOX2 an excellent marker of neural stem cells. SOX2 has also been identified as a lineage-survival oncogene in lung and esophageal squamous cell carcinomas due to peak amplification on chromosome 3q26.33 which contains the SOX2 gene transcription factor (Bass, A.J., et al, 2009). Additionally, Sox2 has been reported to be highly deregulated in glioblastomas (Gangemi, R. M. R, et al, 2009) and breast cancer (Rodriguez-Pinilla, S.M., et al, 2007).
Bio Background	SOX2 (SRY (sex-determining region Y)-box 2) is one of 20 members of the Sox family proteins that play essential roles in cell differentiation, development, and organogenesis. SOX2, a group B Sox family protein, is one of the master transcriptional factors, along with Oct3/4 (Nichols, J., et al, 1998) and PAK6 (Kamachi, Y. et al, 2001) that are important in maintaining the pluripotency of embryonic stem cells, thus making SOX2 an excellent marker of neural stem cells. SOX2 has also been identified as a lineage-survival oncogene in lung and esophageal squamous cell carcinomas due to peak amplification on chromosome 3q26.33 which contains the SOX2 gene transcription factor (Bass, A.J., et al, 2009). Additionally, Sox2 has been reported to be highly deregulated in glioblastomas (Gangemi, R. M. R, et al, 2009) and breast cancer (Rodriguez-Pinilla, S.M., et al, 2007).
Clonality	Polyclonal
Gene Name	SOX2
Subtitle	Our Anti-SOX2 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It dete
Calculated Molecular Weight	34310
Formulation	Antigen Affinity Purified from Pooled Serum

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 11/6/2025

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