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CDKN1A Antibody (C-term)

CDKN1A Antibody (C-term)

Item no.	ABC-AP20797c
Manufacturer	Abcepta
Amount	400 ul
Category	Oncology Antibodies By Cell Type Carcinoma Hematology Lymphoma Melanoma Sarcoma Cell Biology Cell Status Apoptosis Western Blot Senescence Primary Antibodies By Organ Lung Cancer
Type	Antibody Polyclonal
Applications	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Harper J.W.,et al.Cell 75:805-816(1993). El-Deiry W.S.,et al.Cell 75:817-825(1993). Xiong Y.,et al.Nature 366:701-704(1993). Jiang H.,et al.Mol. Cell. Differ. 1:285-299(1993). Jiang H.,et al.Oncogene 10:1855-1864(1995).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Cyclin-dependent kinase inhibitor 1,CDK-interacting protein 1,Melanoma differentiation-associated protein 6,MDA-6,p21,CDKN1A,CAP20,CDKN1,CIP1,MDA6,PIC1,SDI1,WAF1
Available
Manufacturer - Category	Primary Antibodies; Cancer; Cell Biology; Interleukin signaling
Manufacturer - Targets	This CDKN1A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 133-164 amino acids from the C-terminal region of human CDKN1A.
Bio Background	May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin- dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D- CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB43822
Gene Name	CDKN1A
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	18119
Antigen Source	HUMAN

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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