Comparison

CD276 Antibody

Item no. ABC-AP22450a-ev
Manufacturer Abcepta
Amount 50 ul
Category
Type Antibody Polyclonal
Applications WB
Specific against Human (Homo sapiens)
Host Rabbit
Citations Chapoval A.I.,et al.Nat. Immunol. 2:269-274(2001).
Steinberger P.,et al.J. Immunol. 172:2352-2359(2004).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Otsuki T.,et al.DNA Res. 12:117-126(2005).
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias CD276 antigen,4Ig-B7-H3,B7 homolog 3,B7-H3,Costimulatory molecule,CD276,CD276,B7H3
Available
Manufacturer - Category
Primary Antibodies; Cancer; Immunology; Stem Cells
Manufacturer - Isotype
Rabbit Ig
Manufacturer - Targets
This CD276 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from the human region of human CD276.
Bio Background
May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.
Clonality
Polyclonal
Polyclonal Antibody Additonal Information
R03087
Gene Name
CD276
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Calculated Molecular Weight
57235
Antigen Source
HUMAN
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution
WB: 1:1000
Antigen Type
Recombinant Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ul
Available: In stock
available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?
 
Close