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CD36 (Platelet & Microvessel Marker)(1A7), CF740 conjugate, 0.1mg/mL

CD36 (Platelet & Microvessel Marker)(1A7), CF740 conjugate, 0.1mg/mL

Item no.	B-BNC740299-500
Manufacturer	Biotium
Amount	500 uL
Category	Neuroscience Neuroinflammation Aging & Neurological Disorders Antibodies Immunoprecipitation Western Blot Primary Antibodies
Type	Antibody Monoclonal
Applications	WB, IP
Clone	1A7
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2b Kappa
Citations	Am J Pathol (1999) 155(2): 441-452. (WB)Am J Pathol (2003) 162(3): 771-779. (functional studies, IP)
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Shipping Condition	Room temperature
Available
Manufacturer - Type	Primary
Manufacturer - Applications	Functional studies (published), IP (published), WB (published)
Manufacturer - Category	Primary Antibodies Only
Manufacturer - Targets	CD36
Manufacturer - Conjugate / Tag	CF740
Manufacturer - Host	Mus musculus (mouse), Bos taurus (bovine)
Shipping Temperature	Room temperature
Storage Conditions	Store at 2 to 8°C\|Protect fluorescent conjugates from light 2°C to 8°C
Molecular Weight	80-90 kDa
Manufacturer - Research Area	Immunology\|Inflammation
Description	This antibody recognizes a protein of 80-90 kDa, identified as CD36. It is expressed on platelets, monocytes and macrophages, microvascular endothelial cells, erythrocyte precursors, mammary epithelial cells, and some macrophage derived dendritic cells. CD36 acts as a receptor for thrombospondin (TSP), collagen types I, IV and V, P. falciparum malaria-infected erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL) and recognition of apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischemia observed in sickle cell disease and cerebral malaria. Note that 1-4% of Japanese and East Asia population lack CD36.
Product origin	Animal
Ingredient of biological origin	Mus musculus (mouse), Bos taurus (bovine)
Special handling for PI and label	Protect from light
Undated stability guarantee in PI	2 years
Stability at RT during shipping (protected from light)	Stable at room temperature or 37°C (98°F) for 7 days.
UNSPSC Commodity	41116161
UNSPSC Commodity Title	Primary and secondary antibodies for multiple methodology immunostaining detection application
Classified or regulated chemicals	0.05% sodium azide (CAS 26628-22-8)
Concentration	0.1 mg/mL
Storage buffer	PBS, 0.1% rBSA, 0.05% azide
Dated shelf life printed on label	Guaranteed for at least 24 months from date of receipt when stored as recommended
Immunogen (Secondaries, for anti tag only)	Human CD36 from platelets
Clonality	Monoclonal
Regulatory Status	For research use only (RUO)
Human Gene Symbol	CD36
Unigene	120949
Positive Control	HEL or U937 cells. Platelets, monocytes, macrophages, microvascular endothelial cells in a tonsil.
Antibody target cellular localization	Plasma membrane
Cell tissue expression	Platelets\|Erythrocyte precursors\|Mammary gland\|Microvascular endothelial cells\|Monocytes/macrophages
Antibody applications	Functional studies (published), IP (published), WB (published)
Antibody application notes	Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody\|Flow cytometry: 0.5-1 ug/million cells\|Functional Studies Order Ab without Azide\|Immunofluorescence: 0.5-1 ug/mL\|Optimal dilution for a specific application should be determined by user
Expected Antibody Applications	Functional studies (published for clone)\|IP (published for clone)\|WB (published for clone)
Manufacturer - Synonym	Adipocyte membrane protein, CHDS7, Collagen receptor, platelet, fatty acid translocase (FAT), Fatty acid transport protein, glycoprotein iiib (GP IIIb), PAS IV, PAS-4, pas4 protein, platelet collagen receptor, Platelet glycoprotein 4, scarb3, Scavenger receptor class B member 3, thrombospondin receptor
Manufacturer - Antibody Reactivity	CD36
Antibody number	#0299

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

B-BNC740299-500-datasheet.pdf

B-BNC740299-500-safety-datasheet.pdf