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SOX2 (Transcription Factor) (SOX2/1791), CF740 conjugate, 0.1mg/mL

SOX2 (Transcription Factor) (SOX2/1791), CF740 conjugate, 0.1mg/mL

Item no.	B-BNC741791-100
Manufacturer	Biotium
Amount	100 uL
Category	Oncology Neuroscience Neural Lineage Markers Antibodies By Cell Type Carcinoma Immunohistochemistry Western Blot Primary Antibodies Calcium Binding Protein Markers Interneuron Markers
Type	Antibody Monoclonal
Applications	WB, IHC
Clone	SOX2/1791
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2b Kappa
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	ANOP3,Delta EF2a,MCOPS3 (Microphthalmia Syndromic type 3),SOX-2,SRY (sex determining region Y) box 2,SRY related HMG box 2,Transcription factor SOX-2,ysb
Shipping Condition	Room temperature
Available
Manufacturer - Type	Primary
Manufacturer - Applications	IHC, FFPE (verified), WB (verified)
Manufacturer - Category	Primary Antibodies Only
Manufacturer - Targets	SOX2
Manufacturer - Conjugate / Tag	CF740
Manufacturer - Host	Mus musculus (mouse), Bos taurus (bovine)
Shipping Temperature	Room Temperature (Next day)
Storage Conditions	Store at 2 to 8°C\|Protect fluorescent conjugates from light
Molecular Weight	34 kDa
Manufacturer - Research Area	Stem cells\|Transcription factors
Description	SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. At present, 30 Sox genes have been identified. SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product origin	Animal
Ingredient of biological origin	Mus musculus (mouse), Bos taurus (bovine)
Special handling for PI and label	Protect from light
Undated stability guarantee in PI	2 years
Stability at RT during shipping (protected from light)	Stable at room temperature or 37°C (98°F) for 7 days.
UNSPSC Commodity	41116161
UNSPSC Commodity Title	Primary and secondary antibodies for multiple methodologyimmunostaining detection application
Classified or regulated chemicals	0.05% sodium azide (CAS 26628-22-8)
Concentration	0.1 mg/mL
Storage buffer	PBS, 0.1% rBSA, 0.05% azide
Dated shelf life printed on label	Guaranteed for at least 24 months from date of receipt when stored as recommended
Immunogen (Secondaries, for anti tag only)	Recombinant human SOX2 protein fragment (aa176-305) (exact sequence is proprietary)
Clonality	Monoclonal
Regulatory Status	For research use only (RUO)
Human Gene Symbol	SOX2
Unigene	518438
Positive Control	MCF-7 cells or Cervical carcinoma
Antibody target cellular localization	Nucleus
Cell tissue expression	Stem cells
Validated in protein array	Monospecific
Antibody applications	IHC, FFPE (verified)\|WB (verified)
Verified antibody applications	IHC (FFPE) (verified)\|WB (verified)
Antibody application notes	Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody\|Immunofluorescence: 1-2 ug/mL\|ELISA: 2-4 ug/mL for coating order Ab without BSA\|Immunohistology (formalin): 0.5-1 ug/mL\|Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min\|Flow Cytometry 0.5-1 ug/million cells/0.1 mL\|Western blotting 0.5-1 ug/mL\|Optimal dilution for a specific application should be determined by user
Manufacturer - Antibody Reactivity	SOX2
Antibody number	#1791

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

B-BNC741791-100-datasheet.pdf

B-BNC741791-100-safety-datasheet.pdf