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Anti-CLN3 Antibody

Anti-CLN3 Antibody

Item no.	73-390
Manufacturer	Antibodies Incorporated
Amount	5 mL
Category	Antibodies Immunocytochemistry Primary Antibodies Immunoblot
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, ICC
Clone	N380/87
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Battenin (Batten disease protein) (Protein CLN3)
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibody
Manufacturer - Targets	CLN3
Country of Origin	United States
Shipping Temperature	Shipped on ice packs
Storage Conditions	Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight	55 kDa
Manufacturer - Research Area	Rare Diseases
Expiration	24 months from date of receipt
Immunogen	Fusion protein amino acids 1-37, 59-98, 149-179, 233-277, 299-357 and 379-406 (non-helical domains) of human CLN3 (accession number Q13286) produced recombinantly in E. Coli
Immunogen Species	Human
Description	Our Anti-CLN3 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N380/87. It detects human CLN3, and is TC supernatant. It is great for use in ICC, WB.
Target Description	Ceroid-lipofuscinosis neuronal protein 3, Battenin or CLN3 is encoded by the gene CLN3 and is a member of the CLN protein family. CLN3 is thought to be involved in intracellular trafficking and lysosomal function. Mutations in a CLN related gene can result in neuronal ceroid lipofuscinoses or Batten disease, a group of rare, often fatal lysosomal storage diseases. CLN3 plays a role in the transport of late endosomes and lysosomes. CLN3 is widely expressed in tissues
Clonality	Monoclonal
Manufacturer - Specificity	Does not cross-react with other CLN proteins
Concentration	Lot dependent
Form	TC Supernatant
Buffer	Supernatant is provided in cell culture medium with 0.1% sodium azide as anti-microbial
Production Notes	Supernatant is harvested from hybridoma cells grown under standard cell culture conditions
Quality Control	Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
Quality Control: Application	ICC
Usage Statement	These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement	We produce our CLN3 mouse monoclonal primary antibody from hybridoma clone N380/87. It is great in ICC, WB and is TC supernatant.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5 mL

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Delivery expected until 9/11/2025

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