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Anti-ANO5/TMEM16E Antibody

Anti-ANO5/TMEM16E Antibody

Item no.	75-410
Manufacturer	Antibodies Incorporated
Amount	100 uL
Category	Antibodies Immunocytochemistry Primary Antibodies Immunoblot
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, ICC
Clone	N421A/85
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Anoctamin-5 (Gnathodiaphyseal dysplasia 1 protein) (Transmembrane protein 16E)
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibody
Manufacturer - Targets	ANO5/TMEM16E
Country of Origin	United States
Shipping Temperature	Shipped on ice packs
Storage Conditions	Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight	110 kDa
Manufacturer - Research Area	Ion Channels and Modulators, Other Ion Channels
Expiration	24 months from date of receipt
Immunogen	Fusion protein amino acids 1-299 (cytoplasmic N-terminus) of human ANO5 (accession number Q75V66) produced recombinantly in E. Coli
Immunogen Species	Human
Description	Our Anti-ANO5/TMEM16E mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N421A/85. It detects human ANO5/TMEM16E, and is purified by Protein A chromatography. It is great for use in ICC, WB.
Target Description	Anoctamin-5, Transmembrane Protein 16E or -ANO5/TMEM16E is encoded by the gene ANO5. ANO5 belongs to the anoctamin family of membrane proteins many of which are calcium-activated chloride channels. ANO5 does not exhibit this channel activity. ANO5 is expressed in brain, heart, kidney, lung, skeletal muscle as well as other tissues. Diseases associated with ANO5 include Gnathodiaphyseal Dysplasia and Miyoshi Muscular Dystrophy 3.
Clonality	Monoclonal
Manufacturer - Specificity	Does not cross-react with ANO6/TMEM16F
Concentration	1 mg/mL
Form	Purified by Protein A chromatography
Buffer	10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Production Notes	Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Quality Control	Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
Quality Control: Application	ICC
Dilution Range: WB	1:1000
Dilution Range: ICC	1:100
Usage Statement	These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement	We produce our ANO5/TMEM16E mouse monoclonal primary antibody from hybridoma clone N421A/85. It is great in ICC, WB and is purified by Protein A chromatography.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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Delivery expected until 10/9/2025

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