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Anti-GABA-A-R-Pi Antibody

Anti-GABA-A-R-Pi Antibody

Item no.	75-419
Manufacturer	Antibodies Incorporated
Amount	100 uL
Category	Antibodies Immunocytochemistry Primary Antibodies Immunoblot
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IHC, ICC
Clone	N431/64
Specific against	Human (Homo sapiens), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG2a
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Gamma-aminobutyric acid receptor subunit pi (GABA(A) receptor subunit pi)
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibody
Manufacturer - Targets	GABA-A-R-Pi
Country of Origin	United States
Shipping Temperature	Shipped on ice packs
Storage Conditions	Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight	45 kDa
Manufacturer - Research Area	Neurotransmitter Receptors
Expiration	24 months from date of receipt
Immunogen	Fusion protein amino acids 22-242 (extracellular N-terminus) of human GABA-A receptor Pi (accession number O00591) produced recombinantly in E. Coli
Immunogen Species	Human
Description	Our Anti-GABA-A-R-Pi mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N431/64. It detects human GABA-A-R-Pi, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.
Target Description	Gamma-aminobutyric acid receptor subunit pi or GABA AR Pi is encoded by the gene GABRP. GABA A receptors are members of the Cys-loop family of ligand-gated ion channels. GABA AR pi is a subunit of the pentameric GABA receptors where GABA is the major inhibitory neurotransmitter in the vertebrate brain and mediates neuronal inhibition by binding to the GABA receptor and opening an integral chloride channel. GABA AR Pi has been found in tissues including the uterus, ovaries lung, thymus and prostate.
Clonality	Monoclonal
Manufacturer - Specificity	Does not cross-react with GABAARDelta
Concentration	1 mg/mL
Form	Purified by Protein A chromatography
Buffer	10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Production Notes	Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Quality Control	Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
Quality Control: Application	ICC
Usage Statement	These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement	We produce our GABA-A-R-Pi mouse monoclonal primary antibody from hybridoma clone N431/64. It is great in IHC, ICC, WB and is purified by Protein A chromatography.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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Delivery expected until 10/9/2025

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