Comparison

Anti-GABA-A-R-Epsilon Antibody

Item no. 75-398
Manufacturer Antibodies Incorporated
Amount 100 uL
Category
Type Antibody Monoclonal
Format Liquid
Applications WB, IHC, ICC
Clone N413/67
Specific against Human (Homo sapiens), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG2a
Conjugate/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Gamma-aminobutyric acid receptor subunit epsilon (GABA(A) receptor subunit epsilon)
Shipping Condition Cool pack
Available
Manufacturer - Type
Primary Antibody
Manufacturer - Targets
GABA-A-R-Epsilon
Country of Origin
United States
Shipping Temperature
Shipped on ice packs
Storage Conditions
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight
60 kDa
Manufacturer - Research Area
Neurotransmitter Receptors
Expiration
24 months from date of receipt
Immunogen
Fusion protein amino acids 27-253 (extracellular N-terminus) of human GABA-A receptor Epsilon (accession number P78334) produced recombinantly in E. Coli
Immunogen Species
Human
Description
Our Anti-GABA-A-R-Epsilon mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N413/67. It detects human and rat GABA-A-R-Epsilon, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.
Target Description
Gamma-aminobutyric acid receptor subunit epsilon or GABA AR epsilon is encoded by the gene GABRE. GABA A receptors are members of the Cys-loop family of ligand-gated ion channels. GABA AR epsilon is a subunit of the pentameric GABA receptors where GABA is the major inhibitory neurotransmitter in the vertebrate brain and mediates neuronal inhibition by binding to the GABA receptor and opening an integral chloride channel. GABA AR epsilon is found expressed in many tissues including adult heart, placenta and adult brain. In brain, GABA AR epsilon is expressed at the cell junction, synapse, postsynaptic cell membrane and cytoplasmic vesicle membrane.
Clonality
Monoclonal
Manufacturer - Specificity
No cross-reactivity reported
Concentration
1 mg/mL
Form
Purified by Protein A chromatography
Buffer
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Production Notes
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Quality Control
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
Quality Control: Application
WB Brain
Usage Statement
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement
We produce our GABA-A-R-Epsilon mouse monoclonal primary antibody from hybridoma clone N413/67. It is great in IHC, ICC, WB and is purified by Protein A chromatography.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 uL
Available: In stock
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