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Immunogen:Fusion protein amino acids 1-544 (full-length) of rat RGS14 (also known as Regulator of G-protein signaling 14, RAP1/RAP2-interacting protein and RPIP1, accession number O08773)Mouse: 95% identity (524/547 amino acids identical)Human: 86% identity (475/547 amino acids identical)< 45% identity with RGS12 and other RGS proteinsEpitope mapped to within amino acids 444-490 (between 2nd Ras-binding & GoLoco domains, PDAKTREASSIPPCRSQGCLPRTQTKDSHLPPLSSSLSVEDASGSTG, 2014 Evans et al J Comp Neurol)Mouse: 85% identity (40/47 amino acids identical)Human: 51% identity (24/47 amino acids identical)
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