Anti-KChIP3 K+ Channel Antibody

Primary Antibody

United States

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Ion Channels and Modulators, K+ Channels

Fusion protein amino acids 1-256 (full length) of rat Calsenillin/DREAM/KChIP3 (accession number Q9JM47) produced recombinantly in E. Coli

Kchip3 potassium channel, also known as Kv channel-interacting protein 3, Kcnip3, DREantagonist modulator and Dream is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin or neuronal calcium sensor (NCS) family branch of the EF-hand superfamily. Kchip3 is an integral subunit component of native Kv4 channel complexes that may regulate A-type currents and function as a calcium regulated transcriptional repressor. Kchip3 is detected in brain, specifically in the cortex, thalamus, dentate gyrus and cerebellum and can be found throughout the cell. It is also found in other tissues at low levels. Diseases associated with KCNIP3 include alzheimer disease.

No cross-reactivity against rat KChIPs 1, 2, 4

Purified by Protein A chromatography

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.4

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

1:1000

1:250

We produce our KChIP3 K+ channel mouse monoclonal primary antibody from hybridoma clone K66/38. It is great in IHC, ICC, IP, WB and is purified by Protein A chromatography.