Item no. |
75-006 |
Manufacturer |
Antibodies Incorporated
|
Amount |
100 uL |
Category |
|
Type |
Antibody Monoclonal |
Format |
Liquid |
Applications |
WB, IP, IHC, ICC, CHIP |
Clone |
K55/82 |
Specific against |
Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus) |
Host |
Mouse |
Isotype |
IgG2a |
Conjugate/Tag |
Unconjugated |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
Kv channel-interacting protein 1 (KChIP1) (A-type potassium channel modulatory protein 1) (Potassium channel-interacting protein 1) |
Shipping condition |
Cool pack |
Available |
|
Manufacturer - Type |
Primary Antibody |
Manufacturer - Targets |
Pan-KChIP K+ channel |
Country of Origin |
United States |
Shipping Temperature |
Shipped on ice packs |
Storage Conditions |
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap. |
Molecular Weight |
33 kDa (KChIP2), 25 kDa (KChIP3/4), 22 kDa (KChIP1) |
Manufacturer - Research Area |
Ion Channels and Modulators, K+ Channels |
Expiration |
24 months from date of receipt |
Immunogen |
Fusion protein amino acids 1-216 (full length) of rat KChIP1b (accession number Q8R426) produced recombinantly in E. Coli |
Immunogen Species |
Rat |
Target Description |
The Kv channel-interacting proteins (KChIP1, kChIp2, kChIp3, and kChIp4) are members of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin or neuronal calcium sensor (NCS) family branch of the EF-hand superfamily. They serve as auxiliary channel subunits and interact with Kv4 alpha subunits to form native Kv4 channel complexes. KChiP subunits regulate Kv4 channels through various mechanisms including altering: channel density, inactivation kinetics, rate of recovery from inactivation, and cell surface delivery. |
Clonality |
Monoclonal |
Manufacturer - Specificity |
No cross-reactivity reported |
Concentration |
1 mg/mL |
Form |
Purified by Protein A chromatography |
Manufacturer - Format |
Liquid |
Buffer |
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.4 |
Production Notes |
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody. |
Quality Control |
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band. |
Quality Control: Application |
WB Brain |
Dilution Range: WB |
1:1000 |
Dilution Range: IHC |
1:250 |
Dilution Range: ICC |
1:250 |
Dilution Range: IP |
5 µg |
Usage Statement |
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans. |
Manufacturer - Statement |
We produce our Pan-KChIP K+ channel mouse monoclonal primary antibody from hybridoma clone K55/82. It is great in CHiP, IHC, ICC, IP, WB and is purified by Protein A chromatography. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.