Item no. |
75-011 |
Manufacturer |
Antibodies Incorporated
|
Amount |
100 uL |
Category |
|
Type |
Antibody Monoclonal |
Format |
Liquid |
Applications |
WB, IP, IHC, ICC |
Clone |
K7/45 |
Specific against |
Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus) |
Host |
Mouse |
Isotype |
IgG1 |
Conjugate/Tag |
Unconjugated |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
Potassium voltage-gated channel subfamily A member 5 (RCK7) (RK4) (Voltage-gated potassium channel subunit Kv1.5) |
Shipping condition |
Cool pack |
Available |
|
Manufacturer - Type |
Primary Antibody |
Manufacturer - Targets |
Kv1.5 K+ channel |
Country of Origin |
United States |
Shipping Temperature |
Shipped on ice packs |
Storage Conditions |
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap. |
Molecular Weight |
70 kDa |
Manufacturer - Research Area |
Ion Channels and Modulators, K+ Channels |
Expiration |
24 months from date of receipt |
Immunogen |
Fusion protein amino acids 542-602 (cytoplasmic C-terminus) of rat Kv1.5 (accession number P19024) produced recombinantly in E. Coli |
Immunogen Species |
Rat |
Target Description |
Potassium voltage-gated channel subfamily A member 5 or Kv1.5 is encoded by the gene KCNA5. Kv1.5 is a potassium channel subunit is a member of the potassium channel, voltage-gated, shaker-related subfamily. Potassium channels form homotetrameric and heterotetrameric channels in the membrane with various other related proteins, including KCNA2, KCNA4, KCNA5, KCNA6, KCNA7. Kv1.5 is expressed in heart, including the atria nd ventricles. Kv1.5 channels are also expressed in many other organs, such as pulmonary arteries, brain, skeletal muscle. Diseases associated with KCNA5 include Familial Atrial Fibrillation and insulinoma. |
Clonality |
Monoclonal |
Manufacturer - Specificity |
No cross-reactivity reported |
Concentration |
1 mg/mL |
Form |
Purified by Protein A chromatography |
Manufacturer - Format |
Liquid |
Buffer |
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.4 |
Production Notes |
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody. |
Quality Control |
Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern. |
Quality Control: Application |
ICC |
Dilution Range: WB |
1:500 |
Dilution Range: IHC |
1:2000 |
Dilution Range: ICC |
1:100 |
Dilution Range: IP |
2 µg |
Usage Statement |
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans. |
Manufacturer - Statement |
We produce our Kv1.5 K+ channel mouse monoclonal primary antibody from hybridoma clone K7/45. It is great in IHC, ICC, IP, WB and is purified by Protein A chromatography. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.