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Anti-Pan-Neurofascin Antibody

Anti-Pan-Neurofascin Antibody

Item no.	75-027
Manufacturer	Antibodies Incorporated
Amount	100 uL
Category	Neuroscience Neural Lineage Markers Antibodies Immunohistochemistry Primary Antibodies Immunoblot Neuronal Cell Markers
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IP, IHC, ICC
Clone	L11A/41
Specific against	Human (Homo sapiens), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Neurofascin NF-155 NF-186
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibody
Manufacturer - Targets	Pan-Neurofascin
Country of Origin	United States
Shipping Temperature	Shipped on ice packs
Storage Conditions	Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight	155, 186 kDa (plus additional bands on immunoblot)
Manufacturer - Research Area	Cell Adhesion Molecules, Cell Markers, Neuronal Markers, Axonal Markers
Expiration	24 months from date of receipt
Immunogen	Fusion protein 1066-1174 (intracellular domain common to NF-155 and NF-186) of rat NF-155 (accession number AAL27854) produced recombinantly in E. Coli
Immunogen Species	Rat
Target Description	Neurofascin is encoded by the gene NFASC. Two major isoforms of NeuroFascin are expressed as a result of alternative splicing, NF186 and NF155. These proteins are expressed in the central nervous system. In brain, NF186 is expressed at Nodes of Ranvier andNF155 is expressed in unmyelinated axons. Neuofascin plays a role in cell adhesion and is thought to be involved in processes such as neurite extension, synaptogenesis and myelination. Diseases associated with this gene include Demyelinating Polyneuropathy.
Clonality	Monoclonal
Manufacturer - Specificity	No cross-reactivity reported
Concentration	1 mg/mL
Form	Purified by Protein A chromatography
Buffer	10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.4
Production Notes	Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Quality Control	Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
Quality Control: Application	WB Brain
Usage Statement	These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement	We produce our Pan-Neurofascin mouse monoclonal primary antibody from hybridoma clone L11A/41. It is great in IHC, ICC, IP, WB and is purified by Protein A chromatography.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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Delivery expected until 8/28/2025

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