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Anti-GABA-A-R, Alpha1 Antibody

Anti-GABA-A-R, Alpha1 Antibody

Item no.	75-136
Manufacturer	Antibodies Incorporated
Amount	100 uL
Category	Neuroscience Protein Aggregation, Clearance & Misfolding Antibodies Immunocytochemistry Cardiovascular Research Hypertension Primary Antibodies Immunoblot
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IP, IHC, ICC
Clone	N95/35
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG2a
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Gamma-aminobutyric acid receptor subunit alpha-1 (GABA(A) receptor subunit alpha-1)
Shipping Condition	Cool pack
Available
Specificity	Human, Mouse, Rat, and Xenopus
Manufacturer - Type	Primary Antibody
Manufacturer - Targets	GABA(A)R, Alpha1
Country of Origin	United States
Shipping Temperature	Shipped on ice packs
Storage Conditions	Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight	55 kDa
Manufacturer - Research Area	Neurotransmitter Receptors
Expiration	24 months from date of receipt
Immunogen	Fusion protein amino acids 355-394 of mouse GABA-AR-Alpha1 (accession number P62812) produced recombinantly in E. Coli
Immunogen Species	Mouse
Description	Our Anti-GABA(A)R, Alpha1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N95/35. It is KO validated, detects human and mouse GABA(A)R, Alpha1, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.
Target Description	GABA(A)R, Alpha1 (Gamma-aminobutyric acid receptor subunit alpha-1) makes up two of the five subunits in the membrane bound GABA A receptor, the others being two β2 subunits and a single γ2 subunit. The receptor is a ligand gated chloride ion channel found postsynaptically and binds GABA, the major inhibitory neurotransmitter in the CNS. Mutations in GABA(A)R, Alpha1 have been linked to several types of epilepsy.
Clonality	Monoclonal
Manufacturer - Specificity	No cross-reactivity against GABA-A-R-Alpha2 or -Alpha3
Concentration	1 mg/mL
Form	Purified by Protein A chromatography
Buffer	10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.62
Production Notes	Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Quality Control	Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
Quality Control: Application	WB Brain
Dilution Range: WB	1:500
Dilution Range: IHC	1:500
Dilution Range: ICC	1:250
Usage Statement	These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement	We produce our GABA(A)R, Alpha1 mouse monoclonal primary antibody from hybridoma clone N95/35. It is great in IHC, ICC, WB and is purified by Protein A chromatography.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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Delivery expected until 9/25/2025

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