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Anti-Mitofusin-2 Antibody

Anti-Mitofusin-2 Antibody

Item no.	75-173
Manufacturer	Antibodies Incorporated
Amount	100 uL
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Metabolism Neural Mitochondrial Function Molecular Targets for Neuroscience Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Obesity Immunohistochemistry Immunocytochemistry Cardiovascular Research Atherosclerosis Primary Antibodies Immunoblot
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IHC, ICC
Clone	N153/5
Specific against	Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG2a
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Mitofusin-2 (EC 3.6.5.-) (Hypertension-related protein 1) (Mitochondrial assembly regulatory factor) (HSG protein) (Transmembrane GTPase MFN2)
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibody
Manufacturer - Targets	Mitofusin-2
Country of Origin	United States
Shipping Temperature	Shipped on ice packs
Storage Conditions	Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight	90 kDa
Manufacturer - Research Area	Mitochondrial Biology, Neurodegenerative Disease, Parkinson's Disease
Expiration	24 months from date of receipt
Immunogen	Fusion protein amino acids 370-600 (cytoplasmic N-terminus) of mouse Mitofusin-2 (accession number Q80U63) produced recombinantly in E. Coli
Immunogen Species	Mouse
Description	Our Anti-Mitofusin-2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N153/5. It is KO validated, detects mouse and rat Mitofusin-2, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.
Target Description	Mitofusin 2, or transmembrane GTPase Mfn2 (MFN2) is a mitochondrial membrane protein with GTPase activity that functions to aid mitochondrial clustering and fusion. It may also play a role in mitochondrial metabolism. It is expressed in the outer membrane of mitochondria. MFN2 is expressed in many tissues including the heart, skeletal muscle, tongue, and brain. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI,
Clonality	Monoclonal
Manufacturer - Specificity	No cross-reactivity against Mitofusin-1
Concentration	1 mg/mL
Form	Purified by Protein A chromatography
Buffer	10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.101
Production Notes	Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Quality Control	Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
Quality Control: Application	ICC
Usage Statement	These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement	We produce our Mitofusin-2 mouse monoclonal primary antibody from hybridoma clone N153/5. It is great in IHC, ICC, WB and is purified by Protein A chromatography.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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Delivery expected until 8/28/2025

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