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Anti-PARIS/ZNF746 Antibody

Anti-PARIS/ZNF746 Antibody

Item no.	75-195
Manufacturer	Antibodies Incorporated
Amount	100 uL
Category	Neuroscience Neuroinflammation Neural Mitochondrial Function Targets for Rodent Neurosciences Antibodies Immunocytochemistry Primary Antibodies Immunoblot
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IHC, ICC
Clone	N196/16
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Zinc finger protein 746 (Parkin-interacting substrate) (PARIS)
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibody
Manufacturer - Targets	PARIS/ZNF746
Country of Origin	United States
Shipping Temperature	Shipped on ice packs
Storage Conditions	Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight	60-70 kDa
Manufacturer - Research Area	Transcription Regulation
Expiration	24 months from date of receipt
Immunogen	Fusion protein amino acids 1-322 (N-terminus) of human ZNF746 (accession number Q6NUN9) produced recombinantly in E. Coli
Immunogen Species	Human
Description	Our Anti-PARIS/ZNF746 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N196/16. It detects human, mouse, and rat PARIS/ZNF746, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.
Target Description	Zinc finger protein 746, Parkin-Interacting Substrate or PARIS/ZNF746 is encoded by the gene ZNF746. PARIS is a transcription repressor that binds to a consensus sequence on promoters and represses the expression of a transcriptional coactivator, PGC-1-alpha (PPARGC1A). This protein plays a role in regulation of neuron death. PARIS is found in the cytoplasm and nucleus
Clonality	Monoclonal
Manufacturer - Specificity	Does not cross-react with ZNF783 or ZNF398
Concentration	1 mg/mL
Form	Purified by Protein A chromatography
Buffer	10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.123
Production Notes	Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Quality Control	Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
Quality Control: Application	WB Brain
Usage Statement	These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement	We produce our PARIS/ZNF746 mouse monoclonal primary antibody from hybridoma clone N196/16. It is great in IHC, ICC, WB and is purified by Protein A chromatography.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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Delivery expected until 9/11/2025

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