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Anti-Frataxin Antibody

Anti-Frataxin Antibody

Item no.	75-207
Manufacturer	Antibodies Incorporated
Amount	100 uL
Category	Neuroscience Aging & Neurological Disorders Neural Signaling Antibodies Immunocytochemistry Primary Antibodies Immunoblot
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, ICC
Clone	N191/7
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2b
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Frataxin, mitochondrial (EC 1.16.3.1) (Friedreich ataxia protein) (Fxn) [Cleaved into: Frataxin intermediate form (i-FXN); Frataxin(56-210) (m56-FXN); Frataxin(78-210) (d-FXN) (m78-FXN); Frataxin mature form (Frataxin(81-210)) (m81-FXN)]
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibody
Manufacturer - Targets	Frataxin
Country of Origin	United States
Shipping Temperature	Shipped on ice packs
Storage Conditions	Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight	25 kDa
Manufacturer - Research Area	Mitochondrial Biology, Rare Diseases
Expiration	24 months from date of receipt
Immunogen	Fusion protein amino acids 81-210 (C-terminus) of human Frataxin (accession number Q16595) produced recombinantly in E. Coli
Immunogen Species	Human
Description	Our Anti-Frataxin mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N191/7. It detects human Frataxin, and is purified by Protein A chromatography. It is great for use in ICC, WB.
Target Description	Frataxin is a highly conserved protein found in mitochondria. Frataxin is found many tissues including heart, spinal cord, liver, pancreas, dermal fibroblasts, peripheral blood lymphocytes and skeletal muscles. Frataxin functions as an iron chaperone involved in iron-sulfur biogenesis and heme biosynthesis and plays a role in iron homeostasis. Mutations in the Frataxin gene can result in Friederich ataxia.
Clonality	Monoclonal
Manufacturer - Specificity	No cross-reactivity reported
Concentration	1 mg/mL
Form	Purified by Protein A chromatography
Buffer	10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Production Notes	Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Quality Control	Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
Quality Control: Application	ICC
Usage Statement	These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement	We produce our Frataxin mouse monoclonal primary antibody from hybridoma clone N191/7. It is great in ICC, WB and is purified by Protein A chromatography.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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Delivery expected until 8/28/2025

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