Anti-Gs Protein, Alpha Subunit Antibody

Gs protein, alpha subunit

Shipped on ice packs

45 kDa

24 months from date of receipt

Bovine

Guanine nucleotide-binding protein G(s) subunit alpha isoforms short or Gs protein α subunit is encoded by the gene GNAS. Gsα is one of three subunits that make up a guanine nucleotide binding protein (Gprotein). The other proteins are a beta and a gamma subunit. G proteins are further divided into families depending on the type of α subunit included, G(S)alpha, G(Q)alpha, G(I)alpha, and G(12)alpha. Gsα functions as a transducer of numerous signaling pathways that are controlled by g protein coupled receptors (GPCRs) by coupling receptors to adenylyl cyclase and results in increased levels of the signaling molecule cAMP. Diseases associated with GNAS include Mccune-Albright Syndrome and Progressive Osseous Heteroplasia.

Reacts with both Active and Inactive/QL forms

Purified by Protein A chromatography

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

WB Brain

We produce our Gs protein, alpha subunit mouse monoclonal primary antibody from hybridoma clone N192/12. It is great in ICC, WB and is purified by Protein A chromatography.