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Anti-INPP4b Antibody

Anti-INPP4b Antibody

Item no.	75-218
Manufacturer	Antibodies Incorporated
Amount	100 uL
Category	Oncology Antibodies By Cell Type Immunocytochemistry Primary Antibodies Immunoblot
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, ICC
Clone	N171/17
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Type II inositol 3,4-bisphosphate 4-phosphatase (EC 3.1.3.66) (Inositol polyphosphate 4-phosphatase type II)
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibody
Manufacturer - Targets	INPP4b
Country of Origin	United States
Shipping Temperature	Shipped on ice packs
Storage Conditions	Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight	100 kDa
Manufacturer - Research Area	Cell Signaling
Expiration	24 months from date of receipt
Immunogen	Fusion protein amino acids 395-518 of human INPP4b (accession number O15327) produced recombinantly in E. Coli
Immunogen Species	Human
Description	Our Anti-INPP4b mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N171/17. It detects human INPP4b, and is purified by Protein A chromatography. It is great for use in ICC, WB.
Target Description	Inositol polyphosphate 4-phosphatase type II is encoded by the gene INPP4B. INPP4B is a member of the inositol 3, 4-bisphosphate 4-phosphatase family. INPP4B is an enzyme involved in phosphatidylinositol pathways. This enzyme catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3, 4-bisphosphate, inositol 1, 3, 4-triphosphate, and inositol 3, 4-triphosphate. The lipid phosphatase activity is critical for tumor suppressor function. INPP4B activity modulates cell cycle progression and cell survival. INPP4B is widely expressed with the highest levels occuring in the skeletal muscle and heart. No disorders were found to be associated with INPP4B.
Clonality	Monoclonal
Manufacturer - Specificity	Does not cross-react with INPP4a
Concentration	1 mg/mL
Form	Purified by Protein A chromatography
Buffer	10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Production Notes	Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Quality Control	Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
Quality Control: Application	ICC
Usage Statement	These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement	We produce our INPP4b mouse monoclonal primary antibody from hybridoma clone N171/17. It is great in ICC, WB and is purified by Protein A chromatography.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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Delivery expected until 8/28/2025

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