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Anti-Dopamine D2 Receptor Antibody

Anti-Dopamine D2 Receptor Antibody

Item no.	75-230
Manufacturer	Antibodies Incorporated
Amount	100 uL
Category	Neuroscience Neural Signaling Antibodies Primary Antibodies Immunoblot
Type	Antibody Monoclonal
Format	Liquid
Applications	IHC
Clone	N186/29
Specific against	Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	D(2) dopamine receptor (Dopamine D2 receptor)
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibody
Manufacturer - Targets	Dopamine D2 receptor
Country of Origin	United States
Shipping Temperature	Shipped on ice packs
Storage Conditions	Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight	50 kDa
Manufacturer - Research Area	Neurotransmitter Receptors
Expiration	24 months from date of receipt
Immunogen	Fusion protein amino acids 211-374 (cytoplasmic, long form) of rat Dopamine D2 receptor (accession number P61169) produced recombinantly in E. Coli
Immunogen Species	Rat
Description	Our Anti-Dopamine D2 receptor mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N186/29. It detects mouse and rat Dopamine D2 receptor, and is purified by Protein A chromatography. It is great for use in IHC.
Target Description	Dopamine D2 receptor is encoded by the gene DRD2. DRD2 is a member of the G-protein coupled receptor 1 family that also includes D1, D3, D4 and D5. This G-protein coupled receptor inhibits adenylyl cyclase activity. DRD2 is expressed in the brain, colon, testis, and skeletal muscle tissue. Diseases associated with DRD2 include cocaine dependence, pathological gambling, and delusional disorder.
Clonality	Monoclonal
Manufacturer - Specificity	Reacts with both Long and Short formsDoes not cross-react with Dopamine D3 receptor
Concentration	1 mg/mL
Form	Purified by Protein A chromatography
Buffer	10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Production Notes	Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Quality Control	Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.
Quality Control: Application	IHC
Usage Statement	These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement	We produce our Dopamine D2 receptor mouse monoclonal primary antibody from hybridoma clone N186/29. It is great in IHC and is purified by Protein A chromatography.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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Delivery expected until 8/28/2025

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